What Is The Biggest Reason We Use Animals In Research
Why nosotros apply animals in research
We only apply animals in enquiry when it is absolutely essential and there is no other culling available.
Our animals are cared for by a defended team of highly trained staff
Animals are used in medical enquiry to written report illnesses ranging from heart affliction, stroke, cancer, respiratory diseases such equally asthma and chronic obstructive pulmonary illness (COPD), as well every bit rheumatoid arthritis, HIV, Alzheimer'southward disease and many other atmospheric condition.
All medicines, vaccines, antibiotics and anaesthetics used in the UK accept been adult and tested first in animals. Every bit a result, medical research has improved and saved the lives of millions of people worldwide.
In the UK it's a legal requirement that all medicines must be tested in at least ii species of live animals earlier they are used in humans.
How are animals used to develop new medicines?
Scientists who want to develop new treatments use a number of dissimilar methods.
They may starting time past using a calculator to design a new molecule. Alternatively, they may test the thousands of chemicals already available, extract chemicals from natural products, or make human proteins by genetic engineering science.
After selecting a molecule and investigating how it works and what it does to cells in a test tube, scientists then need to expect at what it does in a existent, live body.
Why is a living trunk needed to carry out inquiry?
A complete living body is very unlike to the conditions found inside cells in a test tube. For instance, a medicine might piece of work well on cells in the laboratory only when it is given to a human, it might be destroyed by the digestive system before information technology reaches the part of the body that the drug is targeting. Only brute experiments assistance to uncover this sort of issue.
Next, safety tests are carried out, to encounter if the medicine causes whatever unexpected reactions such as a skin rash or organ failure. Animate being testing also helps researchers to work out which dose to use in humans.
We only apply animals when information technology is admittedly essential and merely if there is no other culling available.
We only utilise animals when it is absolutely essential and there is no other alternative bachelor.
How practise we ensure the welfare of animals at Queen Mary?
Whatsoever research body that wants to utilise animals in enquiry has to apply to the Regime's Home Part for a licence to exercise so.
The use of animals in research is governed by UK legislation. The UK has some of the strictest rules governing animal research in the world, and the Animals (Scientific Procedures) Human activity 1986 balances the needs for enquiry with the welfare of laboratory animals.
The use of animals is closely monitored and carried out according to strict standards and atmospheric condition set down by the Home Function, the UK's licensing dominance.
While the use of animals is closely governed past legislation, we also do as much as we can to ensure the welfare of the animals in our intendance and provide them with a stimulating environment.
Studying mice has helped researchers develop treatments to ho-hum the progress of multiple sclerosis.
Examples of how animals are used in research at Queen Mary
Preventing organ failure in trauma patients
A common anti-malarial drug, artesunate, could be used to reduce organ failure following a traumatic injury, afterward research showed that it is constructive in treating severe bleeding and blood loss in rats. The drug is condom and cheap and is at present going to be tested in clinical trials in patients with organ injury who are admitted to the Major Trauma Centre at The Royal London Hospital in Whitechapel, Britain.
Slowing the accelerate of multiple sclerosis
Studying mice helps researchers led by Professor David Baker develop treatments to slow the progress of multiple sclerosis, an autoimmune condition in which the immune system attacks the myelin sheath – the layer that surrounds the nerves in the brain and spinal string. There is currently no cure for the illness: people with MS have an average life expectancy of v to ten years shorter than the general population. Researchers at Queen Mary are investigating new drugs to target some of the symptoms and tedious down the progression of the disease.
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How we intendance for our animals
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How nosotros minimise the utilise of animals in our research
Acquire more about Queen Mary's dedication to replace, refine and reduce the number of animals we use in research.
Regulation and ethics
Learn more virtually Queen Mary'south commitment to the highest ethical standards of fauna inquiry
Source: https://www.qmul.ac.uk/research/strategy-support-and-guidance/animal-research/why-we-use-animals-in-research/
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